Metagenoms: Difference between revisions

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* [http://fames.jgi-psf.org/ JGI FAMeS]
* [http://fames.jgi-psf.org/ JGI FAMeS]
* [http://fames.jgi-psf.org/cgi-bin/dataset_desc.pl?dataset=soil JGI SIMHC]
* [http://fames.jgi-psf.org/cgi-bin/dataset_desc.pl?dataset=soil JGI SIMHC]
* [http://nihroadmap.nih.gov/hmp/ Human Microbiome Project]
* [http://nihroadmap.nih.gov/hmp/ Human Microbiome Project @ NIH]
* {http://www.nature.com/nature/journal/v449/n7164/full/nature06244.html HMP Nature article Oct 2007]
 
== HMP ==
* ~10X more bateria than human cells in the body
* small-subunit (16S) ribosomal RNA gene-sequence-based surveys :
  - found in all microorganisms
  - has enough sequence conservation for accurate alignment
  - has enough variation for phylogenetic analyses.
* skin, mouth, oesophagus, stomach, colon and vagina
* largest reported data sets are for the gut
* most of the 10–100 trillion microorganisms in the human gastrointestinal tract live in the colon.
* more than 90% of all phylogenetic types (phylotypes) of colonic bacteria belong to just 2 of the 70 known divisions (phyla) in the domain Bacteria: the Firmicutes and the Bacteroidetes.

Revision as of 14:07, 2 June 2008

Links

HMP

  • ~10X more bateria than human cells in the body
  • small-subunit (16S) ribosomal RNA gene-sequence-based surveys :
 - found in all microorganisms 
 - has enough sequence conservation for accurate alignment 
 - has enough variation for phylogenetic analyses.
  • skin, mouth, oesophagus, stomach, colon and vagina
  • largest reported data sets are for the gut
  • most of the 10–100 trillion microorganisms in the human gastrointestinal tract live in the colon.
  • more than 90% of all phylogenetic types (phylotypes) of colonic bacteria belong to just 2 of the 70 known divisions (phyla) in the domain Bacteria: the Firmicutes and the Bacteroidetes.