Dpuiu definitions: Difference between revisions

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* [http://en.wikipedia.org/wiki/Sensitivity_and_specificity Sensitivity and specificity]
  Sensitivity=TP/(TP+FN)
  Specificity=TN/(TN+FP)
                    status     
  outcome          +    -
  +                TP  FP
  -                FN  TN
  FP: Type I error (P value)
  FN: Type II error
  try to minimize FP => increase specificity
  Sensitive: align as many reads as possible
  Specific:  avoid misalignments
         
----
* [http://en.wikipedia.org/wiki/Functional_genomics Functional genomics]
* [http://en.wikipedia.org/wiki/Functional_genomics Functional genomics]
* [http://en.wikipedia.org/wiki/Molecular_biology Molecular biology]
* [http://en.wikipedia.org/wiki/Molecular_biology Molecular biology]

Revision as of 13:59, 4 December 2008

 Sensitivity=TP/(TP+FN)
 Specificity=TN/(TN+FP)
                   status      
 outcome           +    -
 +                 TP   FP
 -                 FN   TN
 FP: Type I error (P value)
 FN: Type II error
 try to minimize FP => increase specificity 
 Sensitive: align as many reads as possible
 Specific:  avoid misalignments
         










  • Q20: the number of bases in a read that have a quality value greater than 20; quality value of 20, there is a 1 in 100 chance that the base has been misidentified