Difference between revisions of "Francisella tularensis"

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* causative agent of tularemia
 
* causative agent of tularemia
 
* category A biodefense concern because of its ability to cause incapacitating, potentially fatal illness
 
* category A biodefense concern because of its ability to cause incapacitating, potentially fatal illness
 +
* 4 subspecies
 +
 +
  Subspecies                                         Virulence Region
 +
  Francisella tularensis subsp. tularensis (Type A) high         North America,
 +
  Francisella tularensis subsp. holarctica (Type B) moderate North America,Europe, Asia
 +
  Francisella tularensis subsp. novicida         moderate .
 +
  Francisella tularensis subsp. mediasiatica         low         .
  
 
== Data Sources ==
 
== Data Sources ==

Revision as of 13:50, 24 August 2007

Characteristics

  • gamma—proteobacterium
  • one of the most infectious human intracellular pathogens
  • causative agent of tularemia
  • category A biodefense concern because of its ability to cause incapacitating, potentially fatal illness
  • 4 subspecies
 Subspecies	                                        Virulence	Region
 Francisella tularensis subsp. tularensis (Type A)	high	        North America,
 Francisella tularensis subsp. holarctica (Type B)	moderate	North America,Europe, Asia
 Francisella tularensis subsp. novicida	        moderate	.
 Francisella tularensis subsp. mediasiatica	        low	        .

Data Sources

NCBI:

Broad:

Baylor:

JGI:

Read Counts

Type A

  • SCHU_S4 SDRA , Complete (1,892,819 bp) NC_006570
  • FSC198 Univ. of Birmingham , Complete ( 1,892,616 bp) NC_008245
  • WY96-3418 BioHealthBase , Complete (1,898,476 bp) NC_009257
  • FSC033 Broad, Assembly (15 contigs) ***
  • ATCC6223 Baylor (88 contigs) ***

Type B

  • LVS LLNL, Complete (1,895,994 bp) NC_007880
  • OSU18 Baylor, Complete (1,895,727 bp) NC_008369 ***
  • KO97 Baylor (126 contigs) ***
  • MI001730 Baylor (118 contigs) ***
  • OR960246 Baylor (111 contigs) ***
  • RC503 Baylor (115 contigs)
  • 275 Broad (31 contigs) ***
  • FSC022 Broad (19 contigs) ***

Novicida

  • U112 Univ. of Washington, Complete (1,910,031 bp) NC_008601
  • GA99-3548 Broad (18 contigs) ***
  • GA99-3549 Broad (15 contigs) ***

Mediasiatica

No traces available

File Locations on Disk

  • /fs/szdata//ncbi/genomes/Bacteria/Francisella_tularensis
  • ~dpuiu/Data/F_tularensis/
  • /fs/szasmg/Bacteria/F_tularensis

454

Paired End reads:

 * approximately 84-nucleotide DNA fragments 
 * have a 44-mer adaptor sequence in the middle 
 * flanked by a 20-mer sequence on each side. 
 * The two flanking 20-mers are segments of DNA that were originally located approximately 2.5 kb apart in the genome of interest.  
 * The ordering and orienting of contigs generates scaffolds which provide a high-quality draft sequence of the genome.
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