Difference between revisions of "Francisella tularensis"

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   Francisella tularensis subsp. tularensis (Type A) high         North America,
 
   Francisella tularensis subsp. tularensis (Type A) high         North America,
 
   Francisella tularensis subsp. holarctica (Type B) moderate        North America,Europe, Asia
 
   Francisella tularensis subsp. holarctica (Type B) moderate        North America,Europe, Asia
   Francisella tularensis subsp. novicida               moderate        .
+
   Francisella tularensis subsp. novicida                 moderate        .
 
   Francisella tularensis subsp. mediasiatica         low         .
 
   Francisella tularensis subsp. mediasiatica         low         .
  

Revision as of 13:51, 24 August 2007

Characteristics

  • gamma—proteobacterium
  • one of the most infectious human intracellular pathogens
  • causative agent of tularemia
  • category A biodefense concern because of its ability to cause incapacitating, potentially fatal illness
  • 4 subspecies
 Subspecies	                                        Virulence	Region
 Francisella tularensis subsp. tularensis (Type A)	high	        North America,
 Francisella tularensis subsp. holarctica (Type B)	moderate        North America,Europe, Asia
 Francisella tularensis subsp. novicida                 moderate        .
 Francisella tularensis subsp. mediasiatica	        low	        .

Data Sources

NCBI:

Broad:

Baylor:

JGI:

Read Counts

Type A

  • SCHU_S4 SDRA , Complete (1,892,819 bp) NC_006570
  • FSC198 Univ. of Birmingham , Complete ( 1,892,616 bp) NC_008245
  • WY96-3418 BioHealthBase , Complete (1,898,476 bp) NC_009257
  • FSC033 Broad, Assembly (15 contigs) ***
  • ATCC6223 Baylor (88 contigs) ***

Type B

  • LVS LLNL, Complete (1,895,994 bp) NC_007880
  • OSU18 Baylor, Complete (1,895,727 bp) NC_008369 ***
  • KO97 Baylor (126 contigs) ***
  • MI001730 Baylor (118 contigs) ***
  • OR960246 Baylor (111 contigs) ***
  • RC503 Baylor (115 contigs)
  • 275 Broad (31 contigs) ***
  • FSC022 Broad (19 contigs) ***

Novicida

  • U112 Univ. of Washington, Complete (1,910,031 bp) NC_008601
  • GA99-3548 Broad (18 contigs) ***
  • GA99-3549 Broad (15 contigs) ***

Mediasiatica

No traces available

File Locations on Disk

  • /fs/szdata//ncbi/genomes/Bacteria/Francisella_tularensis
  • ~dpuiu/Data/F_tularensis/
  • /fs/szasmg/Bacteria/F_tularensis

454

Paired End reads:

 * approximately 84-nucleotide DNA fragments 
 * have a 44-mer adaptor sequence in the middle 
 * flanked by a 20-mer sequence on each side. 
 * The two flanking 20-mers are segments of DNA that were originally located approximately 2.5 kb apart in the genome of interest.  
 * The ordering and orienting of contigs generates scaffolds which provide a high-quality draft sequence of the genome.
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