Comparative assemblies

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AMOScmp pipeline

Modified parameters

  • Smaller alignement/cluster sizes : default are 20/65 ; drop to 16/16 ; as low as 14/14; 12/12 gives too many spurious alignments:
   -D MINCLUSTER=20 
  • Drop min ovl from 10 to 5:
   -D MINOVL=5 
  • Drop majority from 70 to 50:
   -D MAJORITY=50 
  • Drop wiggle from 15 to 2
   -D ALIGNWIGGLE=2
  • Use promer instead of nucmer: alignement/cluster sizes of 6/11 (in AA)

Multiple references